Emerging Role for
αB-Crystallin as a Therapeutic Agent: Pros and Cons
Author(s):
V.S. Reddy and G.B. ReddyPages 47-61 (15)
Abstract:
HSPB5 or αB-crystallin (αBC) is a major protein
of the vertebrate eye lens belonging to the small heat-shock protein family of
proteins that respond to various stressful conditions. αBC also is found
outside the lens in various non-ocular tissues and acts as a molecular
chaperone by preventing aggregation of proteins, inhibits apoptosis and
inflammation, and maintains cytoskeletal architecture. The αBC protein...
